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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
12.5 DPC

16 matching records from 16 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Kdr  kinase insert domain protein receptor   (Synonyms: Flk1, Flk-1, orv, vascular endothelial growth factor receptor- 2, VEGFR2, VEGFR-2, VEGF receptor-2)
Results  Reference
1J:151060 Ahlbrecht K, Schmitz J, Seay U, Schwarz C, Mittnacht-Kraus R, Gaumann A, Haberberger RV, Herold S, Breier G, Grimminger F, Seeger W, Voswinckel R, Spatiotemporal expression of flk-1 in pulmonary epithelial cells during lung development. Am J Respir Cell Mol Biol. 2008 Aug;39(2):163-70
1*J:69389 Ayadi A, Suelves M, Dolle P, Wasylyk B, Net, an Ets ternary complex transcription factor, is expressed in sites of vasculogenesis, angiogenesis, and chondrogenesis during mouse development. Mech Dev. 2001 Apr;102(1-2):205-8
1*J:25542 Dumont DJ, Fong GH, Puri MC, Gradwohl G, Alitalo K, Breitman ML, Vascularization of the mouse embryo: a study of flk-1, tek, tie, and vascular endothelial growth factor expression during development. Dev Dyn. 1995 May;203(1):80-92
1J:174966 Erskine L, Reijntjes S, Pratt T, Denti L, Schwarz Q, Vieira JM, Alakakone B, Shewan D, Ruhrberg C, VEGF signaling through neuropilin 1 guides commissural axon crossing at the optic chiasm. Neuron. 2011 Jun 9;70(5):951-65
1J:62806 Gad JM, Keeling SL, Shu T, Richards LJ, Cooper HM, The spatial and temporal expression patterns of netrin receptors, DCC and neogenin, in the developing mouse retina. Exp Eye Res. 2000 Jun;70(6):711-22
1J:99584 Hitz C, Vogt-Weisenhorn D, Ruiz P, Wurst W, Floss T, Progressive loss of the spongiotrophoblast layer of Birc6/Bruce mutants results in embryonic lethality. Genesis. 2005 Jun;42(2):91-103
1*J:15281 Moens CB, Stanton BR, Parada LF, Rossant J, Defects in heart and lung development in compound heterozygotes for two different targeted mutations at the N-myc locus. Development. 1993 Oct;119(2):485-99
1*J:82684 Motoike T, Markham DW, Rossant J, Sato TN, Evidence for novel fate of Flk1+ progenitor: Contribution to muscle lineage. Genesis. 2003 Mar;35(3):153-9
1*J:14638 Oelrichs RB, Reid HH, Bernard O, Ziemiecki A, Wilks AF, NYK/FLK-1: a putative receptor protein tyrosine kinase isolated from E10 embryonic neuroepithelium is expressed in endothelial cells of the developing embryo. Oncogene. 1993 Jan;8(1):11-8
1J:134727 Provot S, Zinyk D, Gunes Y, Kathri R, Le Q, Kronenberg HM, Johnson RS, Longaker MT, Giaccia AJ, Schipani E, Hif-1alpha regulates differentiation of limb bud mesenchyme and joint development. J Cell Biol. 2007 May 7;177(3):451-64
1J:22847 Qin Y, Sato TN, Mouse multidrug resistance 1a/3 gene is the earliest known endothelial cell differentiation marker during blood-brain barrier development. Dev Dyn. 1995 Feb;202(2):172-80
1*J:91451 Quinn TP, Peters KG, De Vries C, Ferrara N, Williams LT, Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium. Proc Natl Acad Sci U S A. 1993 Aug 15;90(16):7533-7
1J:314585 Shadad O, Chaulagain R, Luukko K, Kettunen P, Establishment of tooth blood supply and innervation is developmentally regulated and takes place through differential patterning processes. J Anat. 2019 Apr;234(4):465-479
1*J:12605 Yamaguchi TP, Dumont DJ, Conlon RA, Breitman ML, Rossant J, flk-1, an flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors. Development. 1993 Jun;118(2):489-98
1J:85564 Zhang H, Palmer R, Gao X, Kreidberg J, Gerald W, Hsiao L, Jensen RV, Gullans SR, Haber DA, Transcriptional activation of placental growth factor by the forkhead/winged helix transcription factor FoxD1. Curr Biol. 2003 Sep 16;13(18):1625-9
1*J:99650 Zhao L, Wang K, Ferrara N, Vu TH, Vascular endothelial growth factor co-ordinates proper development of lung epithelium and vasculature. Mech Dev. 2005 Jul-Aug;122(7-8):877-86

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory